24/7 BIOPHARMA - issue 1 / October 2024

SUNRESIN NEW MATERIALS

and up to 1.5M in specific applications). The resin demonstrates excellent affinity for the Fc region of mAbs, maintains stable yield and purity across 100 cycles and can be seamlessly integrated with additional chromatography techniques such as IEX, HIC, or SEC to achieve drug-level purity. Sunresin is a trusted partner for biomolecule purification, solid phase synthesis, enzymatic catalysis, ion exchange and adsorption, providing a comprehensive range of resins and expert technical support.

SIMONA SERBAN Global Life Science Applications Director Sunresin New Materials ALESSANDRA BASSO Global Sales and Marketing Director - Life Science Sunresin New Materials

Sunresin offers a broad selection of agarose resins suitable for large biomolecule separation, including various particle sizes for capture, intermediate purification and polishing. These resins include sulfopropyl, quaternary amine with or without dextran extenders, carboxymethyl, DEAE, phenyl, butyl, multimodal and gel filtration resins. These options can be paired with the rProtein A affinity step to achieve mAb purity above 99%.

Conclusion

TONG NIAN GU, LONG LIU, YAN JUN LI Sunresin New Materials

The new rProtein A Seplife Suno agarose affinity resin developed by Sunresin offers high dynamic binding capacity, excellent CIP stability and high tolerance to alkaline solutions (up to 1M NaOH

68 TWENTYFOURSEVENBIOPHARMA Issue 1 / October 2024