24/7 BIOPHARMA - issue 1 / October 2024

INDENA

implementing the use of renewable energy. That’s why Indena is equipping all its European sites with state-of-the-art photovoltaic panels – considering the actual equipment and the upcoming projects, the Indena Group will be equipped with over 4 MW of photovoltaic systems with a total estimated production capability of 4.000.000 kWh per year. All of Indena’s European factories are ISO 14001 Environmental Management System and ISO 45001 Occupational Health and Safety Management System certified. Every action taken in favour of sustainability also enables Indena to be fully reliable in terms of business continuity. More specifically, Indena has the commitment to pursue the adaptation of the production system to EU policies regarding the fight against climate change. The first goals of its commitment and of the related investments are the achievement of a greater energy efficiency in the execution of business activities, an efficient use of resources, and a fundamental change in the overall production process to allow greater energy or resource efficiency. The program includes the following implementations: - For energy efficiency: -2°C high-efficiency chiller, efficient nitrogen production system, high efficiency heat pumps. - For heat and water efficiency: 7-12°C high efficiency chiller. - For renewable energy: an additional 1.5 MW solar photovoltaic power plant. The attention paid by Indena to the goals of business continuity: working on risk mitigation, the development of a dedicated plan, the capability to resume operations in a timely manner and the protection of critical assets (including data, personnel and technology infrastructure), makes Indena a totally reliable partner for all its clients. Moreover, Indena has been awarded the ECOVADIS certification, achieving the Bronze Medal. ECOVADIS recognises the company’s commitment to managing ESG risk and compliance, achieving corporate sustainability goals and driving large-scale impact by fostering improved sustainability performance for the company and its value chain.

Figure 2. P8 plant.

synthesis and purification (small molecules to OEB5), and higher production capacity for products actually made in other departments. More technologies will be added for the chemical synthesis and purification of APIs and HPAPIs: centrifugation under containment (reverse bag centrifuge), reactor loading under containment (glove boxes), isolation and drying on filter dryer, and purification on 2000 low/medium pressure columns (up to 9 bars). For hydrogenation, Indena has recently acquired a Biazzi hydrogenator, able to work up to 10 barg. One of the most important factors for the quality of the CDMO services delivered by Indena is people. It means the human and professional resources of whole teams working on CDMO activities, where lifelong professional experiences are fused with the enthusiasm and fresh skills of many young scientists. Because at Indena, it is well-known that highly qualified, motivated and trained technical staff, supported by a corporate culture, strongly oriented toward quality and rigorous HSE policies, is essential to ensure that operations run safely, seamlessly and efficiently. Indena is also well-supported by a strong regulatory department that continuously interacts globally with the most important national health authorities, such as FDA, EMA, AIFA, ANSN and PDMA. The strengths of Indena’s CDMO offer are then supported by manufacturing excellence programs, the highest equipment standards and qualified human resources. Climate change is one of the most urgent sustainability challenges that people, governments and companies have to face. Among the actions that companies are requested to take is a responsible use of energy. Indena has always been oriented and committed to reducing fossil fuel consumption and use, saving energy, achieving high levels of energy self-production and The importance of people Commitment to sustainability

50 TWENTYFOURSEVENBIOPHARMA Issue 1 / October 2024